Traditional image steganography methods embed secret data into cover images but often face detection by steganalysis tools due to detectable pixel modifications, which increase the risk of data leakage. These techniques also typically degrade image quality and offer limited capacity. To overcome these challenges, a novel approach for medical imaging is proposed, integrating Generative Adversarial Networks (GANs), PatchGAN, Adaptive LSB steganography, and a dual attention mechanism. PatchGAN improves fine-grained texture details, while Adaptive LSB securely embeds sensitive data within the images. The dual attention mechanism highlights critical regions, enhancing both image clarity and diagnostic accuracy. This method improves image quality and security, benefiting clinical decision-making and patient outcomes. The system is evaluated against traditional methods like GAN and IDGAN using metrics such as embedding capacity, classification accuracy (stego, cover, global), and discriminator loss. Results demonstrate that the proposed system outperforms existing techniques, offering significant improvements in both performance and security for medical imaging applications. © 2025 Elsevier B.V., All rights reserved.