Nanocapsules propose a hopeful solution for recuperating the delivery of inadequately bio available medications, providing benefits such as increased solubility, enhanced bioavailability, and targeted delivery. They can summarize a wide range of therapeutic agents, improving efficacy and reducing side effects. Continued advancements in nanotechnology and materials science are enhancing nanocapsule design, opening doors for new treatments. Future research should prioritize optimizing these systems for clinical use and addressing stability and regulatory challenges. The victorious assimilation of nanocapsules into majority medicine could revolutionize treatment options for complex drug formulations. © 2025 Elsevier B.V., All rights reserved.