Snakebites are the most neglected health problem in India. Antivenoms are used in treatment, but since they are mostly unavailable, the mortality rate is even higher in rural areas. The currently available antivenoms are monovalent and polyvalent and are effective against four common snakes in India. In this article, we have reviewed the herbal antivenoms against specific snake species along with their in vitro and in vivo studies and the phytochemicals responsible for antivenom activity. These phytochemicals have been scientifically proven to neutralize the effects of deadly snake venoms and can be used as an adjunct to anti snake venom therapy or can be effectively used to provide proper first aid in snake bite cases to decrease the mortality rates. Studies have been conducted on plant extracts to explore their antivenom activity along with anti myotoxic, anti haemorraghic as well as anti inflammatory activity. These herbs are used ethnopharmacologically by traditional healers for snake envenomations. The review here is a comprehensive approach to the phytochemicals having anti venom activity, however, further studies are needed to gain in-depth knowledge. © 2024 Elsevier B.V., All rights reserved.