A study on serum magnesium, insulin resistance and coronary lipid risk factors in Type 2 diabetes mellitus

Shanmugapriya, V. (55765808200) and Balaji, K. (57197984936) and Gowtham, Anii (56388693900) (2014) A study on serum magnesium, insulin resistance and coronary lipid risk factors in Type 2 diabetes mellitus.

Full text not available from this repository.

Abstract

Introduction: Diabetes Mellitus is a metabolic disease due to absolute or relative insulin deficiency. Magnesium (Mg) plays a key role in regulating insulin action, insulin mediated glucose uptake and in overall carbohydrate metabolism.Aim: This present study was designed to find out serum magnesium level, insulin resistance and coronary lipid risk factors in type 2 diabetic patients.Materials and Methods: 33 known type 2 diabetic patients and 20 controls were evaluated for their fasting and postprandial glucose level, lipid profile, fasting insulin, HbAlc, Body Mass Index (BMI) and cardiac risk factors.Results: The mean duration of diabetes among the patients was 6.03 years. The serum magnesium level among the diabetic patients was 1.86 ± 0.14 mg/dl when compared to the control group 2.3 ±0.14 mg/dl. All the lipid parameters were significantly elevated in diabetic patients than the controls except for HDL-C which was found to have a negative correlation. As expected HbAlc and serum insulin levels were elevated in diabetics than the controls. Serum fasting glucose had negative correlation with magnesium level and positive correlation with insulin level, HbA<inf>1</inf>c, TC, TGL, LDL, VLDL and coronary risk factors like LDL/HDL-C ratio, TC/HDL ratio and Non HDL-C(NHDL).Conclusion: Type 2 diabetic patients were known for hypomagnesaemia and treatment should include dietary modification with magnesium supplementation along with strict blood glucose control and regular monitoring of their lipid status for cardiac complications. © 2021 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects:
Divisions: Medicine > Vinayaka Mission's Kirupananda Variyar Medical College and Hospital, Salem > Biochemistry
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 11 Dec 2025 06:12
URI: https://vmuir.mosys.org/id/eprint/4941

Actions (login required)

View Item
View Item