Introduction Acne vulgaris mostly affects the face resulting in low self esteem, depression and social phobia thereby affecting the quality of life. Chemical peeling is still considered a simple procedure, requiring hardly any instrumentation which is done in day to day practice to treat acne vulgaris. Objective: To compare the efficacy of 30 % salicylic acid peel (SA) versus 20% salicyclic acid peel with 10% mandelic acid peel (SMP) in the treatment of acne vulgaris. Materials and Methods A total of 50 patients were selected and divided into two groups; A (treated with 30% salicylic acid peel) & B (treated with 20% salicyclic acid peel with 10% mandelic acid peel). Data were coded and analyzed. Results Of the 50 participants, 41 completed all four sessions. Among those 41 patients, 23 belonged to group A and 18 belonged to group B. In group A, 51-75 % improvement was noted in 22 (96%) patients and one (4%) had 26-50% improvement. In group B, 51-75 % improvement was noted in 14 (78%) patients, Three (17%) had 26-50 % improvement, one (6%) patient showed less than 25% improvement. Conclusion This study infers that reduction in active acne lesions was much more with 30% salicylic acid peel, whereas postacne melanosis reduced much with the combination peel (SMP). We conclude that both salicylic acid (SA) and Salicylic+Mandelic acid Peel are efficient, well tolerated and reasonably safe procedure that can be used as treatment modality in acne vulgaris. © 2019 Elsevier B.V., All rights reserved.