Artificial intelligence Examination and Enhancement of Multifunctional Drone for Medical The fundamental goal of this paper's research and optimization of effective drones is the prompt software using flight plans that include sensors and a global positioning system (GPS). Drones, which were first created for military use, are now being used for a variety of civilian reasons, especially in the care and medical fields, which are the subject of this study. The medical industry must deal with issues such restricted access to urban areas for vehicle travel, restricted entry into areas where infectious diseases are prevalent, difficult terrain for human access, deployment in conflict zones, lengthy transit times, and limited operating hours. Drone use helps to overcome these obstacles by enabling fast progress in the commercial, industrial, and recreational domains as well as real-time data collecting and cost-effective payload delivery. Drone technology has been slowly incorporated into the medical field, despite its potential. In epidemiological duties such as disease surveillance, catastrophe monitoring, and biological hazard surveillance, drones are indispensable. Drones used for telecommunication improve telemonitoring, perioperative assessments, remote diagnosis, and therapy. Drones also show a great deal of promise as dependable means of delivering drugs, vaccines, emergency medical supplies, laboratory samples, pharmaceuticals, and even patients. The systems Networked for Urban Use: Medical drone networks may be integrated into emergency response and healthcare systems in smart cities in the future. In order to provide vital treatment more quickly than with conventional means, these drones would collaborate with hospitals, ambulances, and first responders. © 2025 Elsevier B.V., All rights reserved.