Synthesis and Pharmacological Investigation of 5-Substituted-3-methylsulfanyl-1H-pyrazole-4-carboxylic Acid Ethyl Esters as New Analgesic and Anti-inflammatory Agents

Dimensions

Gokulan, P. and Jayakar, B. and Alagarsamy, V. and Raja Solomon, V. (2012) Synthesis and Pharmacological Investigation of 5-Substituted-3-methylsulfanyl-1H-pyrazole-4-carboxylic Acid Ethyl Esters as New Analgesic and Anti-inflammatory Agents. Arzneimittelforschung, 62 (10). pp. 457-462. ISSN 0004-4172

Full text not available from this repository.

Abstract

This study synthesized 5-substituted-3-methylsulfanyl-1H-pyrazole-4-carboxylic acid ethyl esters and evaluated their analgesic and anti-inflammatory activity. Compound 4c (5-benzoylamino-3-methylsulfanyl-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester) showed highest activity with mild ulcerogenic potential, indicating its potential as a lead molecule for developing new analgesic and anti-inflammatory agents. © Georg Thieme Verlag KG Stuttgart New York. © 2013 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery
Divisions: Pharmacy > Vinayaka Mission's College of Pharmacy, Salem > Pharmacy
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 10 Dec 2025 06:55
URI: https://vmuir.mosys.org/id/eprint/4254

Actions (login required)

View Item
View Item