As no material is available on medico-legal issues on poisoning cases in this locality, we have decided to research on this subject. Hence, a prospective medico-legal study of 100 poisoning cases admitted to the Maharajah's Institute of Medical Sciences hospital (Vizianagaram) between 2010 - 2015 was undertaken. In this study we found that 72% of cases were due to insecticidal poisoning. Out of total 11 deaths, 8 were due to organophosphates. One of the important findings of this study was that there was no female mortality. We concentrated on medico-legal factors as age, sex, socio-economic conditions etc. hoping that such data would be available to future researchers as reference material. In the concluding paragraphs we have mentioned some applications based on the study. These include the restriction of sale of insecticides for general population and strengthening of treatment facilities at District head quarters hospitals in high risk districts. This would lessen the number of cases and deaths. © 2017 Elsevier B.V., All rights reserved.