A novel cryptographic algorithm, namely Significant Secure Biometric Key (SSBK) algorithm is proposed.The novel algorithm is compared with the existing cryptographic algorithms like Advanced Encryption Standard (AES), key exchange algorithm like Diffie-Helman and also with Symmetric Random Biometric Key (SRBK) algorithm, and finally we prove the proposed algorithm is superior than existing algorithm based on few parameters. A sample plain text is taken and converted to cipher text and the key from the biometric feature is used for encryption and decryption. In the key generation process, the bi-modal biometrics, namely Ear and Lip features are taken. The concatenated key values obtained from ear and lip can be of minimum 8 bits to the maximum of 1024 bits based on the type of algorithm used.