In material applications nano materials and nano crystals are widely used and many utilization in all fields of science and technology. In this study we converted macro crystal into nano crystal by ball milling method, crystals are analysed by XRD method for parameters and the crystal is converted into nano crystals of 45 nm which are used for filter applications and anti diabetic study of the nano crystal inhibition values are increased with proper increase in the value of concentration, IC50 values are 29.8 for Nano crystal of BGHB. © 2023 Elsevier B.V., All rights reserved.