To conserve less energy in vapour compression refrigeration system is the main problem and many researches has been performed to overcome that issue. To enhance Coefficient of Performance of the system and to reduce compressor work dispersion of nanoparticles in the lubricants plays the vital role and lead to a better alternative and can produce remarkable changes. In this study Al2o3/Sio2 nanolubriants used as a alternative for lubricating oil in Vapour compression refrigeration system. These hybrid nanolubricants are prepared by mixing two various nanoparticles at concentrations of 0.4 g/L and 0.6 g/L and refrigerant mass charges of 40 and 60 g of R600a refrigerant. These aluminium oxide and silicon dioxide nanoparticles will be resulted in improved Coefficient of Performance and refrigeration effect. Experiment is performed with 0.4 g/L of Al2o3/0.6 g/L of Sio2 hybrid nanolubricant in R600a refrigeration system. After conducting experiments the performance of the nanolubricant system is compared with system without nanoparticles. By addition it will lead to 30% increase in performance, Cooling capacity by 25% and reduced compressor power consumption of 80 W. © 2023 Elsevier B.V., All rights reserved.