A case–control study to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus

Vijayalakshmi, Lakshmanan and Raj, JosephBabhu Susai and Kavitha, Jayavel and Krishnaraj, Selvaraj and Manovijay, Balagangadharan and Manikandan, Dhanasekaran (2020) A case–control study to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus. Journal of Pharmacy And Bioallied Sciences, 12 (5). p. 389. ISSN 0975-7406

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Abstract

Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus (DM). Materials and Methods: The samples included in the study were divided into two groups: group A, comprises 50 patients with type 2 DM, and group B, comprises 30 subjects who were nondiabetic. A nonrandom consecutive sampling technique was used to enroll the subjects for the study. The χ2 test was used to examine the characteristics of the samples. Results: The results found that there is a significant difference in saliva and swab for Candida growth between patients with type 2 DM and normal healthy individuals. Swab had shown slightly more Candida growth than saliva in group A (type 2 DM). No significant variation in Candida growth was found. Candida krusei was seen in normal healthy individuals alone. In antifungal susceptibility pattern to various antifungal agents, Candida tropicalis has shown a significant result for various antifungal agents whereas Candida albicans and Candida dubliniensis did not show any significant result for various antifungal agents used in group A (patients with type 2 DM). Conclusion: Diabetic individuals who are prone to a hyperglycemic state favors the growth and establishment of Candida species. Although a smaller percentage of multidrug-resistant Candida species has been observed in the saliva of patients with type 2 DM. © 2020 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects: Vinayaka_Mission_Research_Foundation > Dentistry > Vinayaka Mission's Sankarachariyar Dental College, Salem > Periodontology
Divisions: Medicine > Vinayaka Mission's Kirupananda Variyar Medical College and Hospital, Salem > Medicine
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 04 Dec 2025 11:45
URI: https://vmuir.mosys.org/id/eprint/3432

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