Antibacterial and antibiofilm efficacy of quercetin against Pseudomonas aeruginosa and methicillin resistant Staphylococcus aureus associated with ICU infections

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Vijayakumar, Kalidass and Ganesan, Vinitha and Suganya, Kannan (2025) Antibacterial and antibiofilm efficacy of quercetin against Pseudomonas aeruginosa and methicillin resistant Staphylococcus aureus associated with ICU infections. Biofouling, 41 (2). 211 - 224. ISSN 08927014; 10292454

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Abstract

This study evaluates the antimicrobial potential of quercetin against multidrug-resistant pathogens Pseudomonas aeruginosa and MRSA. In vitro assays demonstrated quercetin's inhibition of bacterial motility, biofilm formation, and virulence factors. In vivo experiments with Caenorhabditis elegans showed reduced bacterial colonization. The findings suggest quercetin as a promising therapeutic agent against multidrug-resistant infections in ICU settings.

Item Type: Article
Additional Information: Cited by: 3
Uncontrolled Keywords: antimicrobial activity; bacterial disease; bacterium; biofilm; drug resistance; health risk; motility; nematode; serum; antiinfective agent; quercetin; animal; Caenorhabditis elegans; cross infection; drug effect; drug therapy; human; intensive care unit; methicillin resistant Staphylococcus aureus; microbial sensitivity test; microbiology; physiology; prevention and control; Pseudomonas aeruginosa; Pseudomonas infection; quorum sensing; Staphylococcus infection; Animals; Anti-Bacterial Agents; Biofilms; Cross Infection; Humans; Intensive Care Units; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pseudomonas Infections; Quercetin; Quorum Sensing; Staphylococcal Infections
Subjects: Immunology and Microbiology > Applied Microbiology and Biotechnology
Divisions: Arts and Science > Vinayaka Mission's Kirupananda Variyar Arts & Science College, Salem > Computer Science
Depositing User: Unnamed user with email techsupport@mosys.org
Date Deposited: 26 Nov 2025 09:07
Last Modified: 26 Nov 2025 09:07
URI: https://vmuir.mosys.org/id/eprint/332

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