Introduction: Dental caries is irreversible microbial disease-causing cavitation. It is necessary to restore the cavitated carious lesion with suitable restorative materials. Choice of restorative materials is depending on mechanical properties and biocompat-ibility. Objectives: This study was done to compare the mechanical properties (compressive strength (CS) and diametral tensile strength (DTS)) of GIC, Cention-N and nanohybrid composite restorative materials. Methods: Thirty specimens with 10 in each group were prepared from Glass Ionomer Cement (GIC), Cention-N and nanohybrid composite restorative materials for testing compressive strength and DTS. Results obtained were statistically evaluated by one-way ANOVA and Tukey’s post hoc test at significance (p < 0.001). Results: We observed highest mean compressive strength for Cention-N 248.52±4.28MPa, followed by 203.11±1.35 MPa in Nano hybrid composite and least for GIC i,e 157.32±1.58 MPa, which is statistically significant (P< 0.001). Highest mean diame-tral tensile strength was observed with Cention-N (108.63.76±1.73 MPa) followed by Nanohybrid composite (92.54±1.21MPa) and least with GIC (54.28±1.12MPa) which is statistically significant (P<0.001). Intergroup comparison of compressive and diametral tensile strength was highly significant 0.001. Conclusion: This study indicates the highest compressive and tensile strength with Cention N followed by hybrid composite, and GIC restorative materials. © 2021 Elsevier B.V., All rights reserved.