The regular building structure consists of eccentric or unsymmetrical reinforced concrete lift walls made of shear walls leads to irregular Building in the plan due to uneven distribution of stiffness. Under the circumstance of such buildings located in the high seismic zone, the design engineer's responsibility becomes more challenging. Hence, the designer must understand the seismic response of irregular structures clearly. This research presents a comparative investigation on the lift wall structure located at the concentric and eccentric position, and it is subjected to lateral seismic load according to the Ethiopian building code. Here, a ground plus ten stories residential building is considered for the investigation, and linear static analysis is performed using the finite element method. In a nutshell, the eccentric lift wall is subjected to additional translation bending and rotational bending that produces an induced story deflection, leading to additional material requirement and is expensive compared to the concentric lift wall. © 2021 Elsevier B.V., All rights reserved.