Characterization, Molecular Docking, Antimicrobial and Anticancer Studies on 5-Bromo salicylaldehyde-furan-2-yl-methanamine Condensed Schiff Base Rare Earth Metal Complexes

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Preethi, B. and Jayaprakash, R. and Rani, S. Kutti and Vijayakumar, N. (2021) Characterization, Molecular Docking, Antimicrobial and Anticancer Studies on 5-Bromo salicylaldehyde-furan-2-yl-methanamine Condensed Schiff Base Rare Earth Metal Complexes. Asian Journal of Chemistry, 33 (9). pp. 2127-2134. ISSN 09707077

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Abstract

This work described the synthesis and characterization of 1-(furan-2-yl) methanamine condensed with 5-bromo-2-hydroxybenzaldehyde Schiff base rare earth metal (Ln3+, Pr3+, Nd3+, Sm3+ and Eu3+) complexes. They were characterized using relevant spectral techniques and docked against microbial target proteins (1H9Z, 3ZBO) theoretically. The experimental antibacterial and anticancer activities (HeLa, MCF7) of these metal complexes were investigated for biological efficacy. Out of five metal complexes, Pr3+ complex exposed good biological efficacy result in both assays. © 2021 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects: Chemistry > Inorganic Chemistry
Divisions: Arts and Science > Vinayaka Mission's Kirupananda Variyar Arts & Science College, Salem > Chemistry
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 03 Dec 2025 12:06
URI: https://vmuir.mosys.org/id/eprint/3122

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