Condylar hyperplasia (CH) of the mandible is a rare developmental disorder that results in enlargement of the condyle. It is predominant in females, mostly unilateral and self-limiting. This report presents a case of a 35-year-old female patient with unilateral condylar hyperplasia with an increase in vertical height of mandibular ramus of the affected side. After initial radiographic evaluation, the asymmetry index using a panoramic radiograph was determined and also analyzed using cone-beam computed tomography (CBCT). Condylar dimensions in all the planes were measured for both sides using CBCT. This case report emphasizes the importance of CBCT and its role in the diagnosis and assessment of mandibular condylar hyperplasia. © 2022 Elsevier B.V., All rights reserved.