Targeting Staphylococcus aureus and its biofilms with novel antibacterial compounds produced by Lactiplantibacillus plantarum SJ33

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Ray Mohapatra, Amrita and Harikrishnan, Adhikesavan and Lakshmanan, Divya and Jeevaratnam, Kadirvelu (2022) Targeting Staphylococcus aureus and its biofilms with novel antibacterial compounds produced by Lactiplantibacillus plantarum SJ33. Archives of Microbiology, 204 (1). ISSN 0302-8933

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Abstract

Two novel low molecular weight (LMW) compounds (C1: 254.1141 Da, C2: 234.1658 Da) from Lactiplantibacillus plantarum SJ33 were isolated and evaluated against Staphylococcus aureus biofilms, including MRSA. Compounds demonstrated bactericidal action, reduced biofilm formation, and down-regulated icaC and icaD genes involved in intercellular adhesion. Structural identification was confirmed by RP-HPLC, spectroscopy, and ESI–MS. These LMW compounds show promising anti-biofilm activity. © 2021 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects: Engineering > Engineering
Divisions: Medicine > Aarupadai Veedu Medical College and Hospital, Puducherry
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 02 Dec 2025 09:39
URI: https://vmuir.mosys.org/id/eprint/3038

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