Effect of injection speed of hyperbaric bupivacaine 0.5 in spinal anesthesia on block quality and hemodynamic changes in elective cesarean sections

Naveena, P. and Naveenkumar, P. and Kumar, Arun B. and Shanmugasundaram, Shanu and Choudhary, R. Arbind Kumar and Periasamy, Panneerselvam (2025) Effect of injection speed of hyperbaric bupivacaine 0.5 in spinal anesthesia on block quality and hemodynamic changes in elective cesarean sections. Anaesthesia, Pain and Intensive Care, 29 (1). 105 - 111. ISSN 16078322; 22205799

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Abstract

Spinal anesthesia (SA) with hyperbaric bupivacaine 0.5% is standard for lower segment cesarean sections (LSCS). This study compared the effects of slow versus fast injection speeds on block quality, hemodynamic stability, and recovery. Sixty patients were randomly allocated: Group A received injection over 25 sec, Group B over 50 sec. Outcomes included sensory block onset, maximum block level, hemodynamic trends, recovery parameters, analgesia requirements, and adverse events. Results showed no significant differences in block onset, maximum sensory level, hemodynamic stability, or recovery times between the groups. Rescue analgesia and adverse events were equivalent. Conclusion: Slow and fast injection speeds demonstrated equivalent efficacy and safety, supporting flexibility based on clinical context.

Item Type: Article
Additional Information: Cited by: 0; All Open Access; Gold Open Access
Uncontrolled Keywords: bupivacaine; ondansetron; adult; American Society of Anaesthesiologists score; analgesia; analgesic activity; Article; benchmarking; bradycardia; Bromage scale; cesarean section; clinical practice; controlled study; dermatome; diastolic blood pressure; double blind procedure; female; glucose blood level; hemodynamic parameters; hemodynamics; human; hypotension; incidence; kidney function test; major clinical study; male; mean arterial pressure; mobilization; obstetric anesthesia; oxygen saturation; postoperative pain; prospective study; randomized controlled trial; spinal anesthesia; visual analog scale
Subjects: Medicine > Anaesthesiology and Pain Medicine
Divisions: Medicine > Vinayaka Mission's Kirupananda Variyar Medical College and Hospital, Salem > Anaesthesiology
Depositing User: Unnamed user with email techsupport@mosys.org
Date Deposited: 26 Nov 2025 09:27
Last Modified: 26 Nov 2025 09:27
URI: https://vmuir.mosys.org/id/eprint/288

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