Otitis externa (OE), or swimmer's ear, is a common inflammatory condition affecting the external auditory canal, leading to symptoms such as ear pain, itching, and hearing impairment. It is caused by various pathogens, including Pseudomonas aeruginosa and Staphylococcus aureus. This study compared the clinical effectiveness of antibiotic-steroid ointment wicks versus antibiotic-steroid drops-soaked gel foam in pain management for patients with otitis externa. One hundred patients, aged 18–60 years, were randomly assigned to two groups: Group A received ointment wicks, and Group B received drops-soaked gel foam. Pain levels were assessed on Days 1, 3, and 5 using standard scales. Group A experienced a significant reduction in pain compared to Group B. The study demonstrates that antibiotic-steroid ointment wicks are more effective than drops-soaked gel foam in reducing pain associated with acute otitis externa.