Anticancer, anti-diabetic, antimicrobial activity of zinc oxide nanoparticles: A comparative analysis

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Chandrasekaran, Senthilkumar and Anusuya, Shanmugam and Anbazhagan, Venkattappan (2022) Anticancer, anti-diabetic, antimicrobial activity of zinc oxide nanoparticles: A comparative analysis. Journal of Molecular Structure, 1263. p. 133139. ISSN 00222860

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Abstract

This study synthesized ZnO nanoparticles (ZnO NPs) via chemical precipitation and green methods using Vinca rosea leaf extract. Characterization (UV–Vis, PL, FTIR, XRD, HR-TEM, SEM) confirmed hexagonal ZnO NPs (16–41 nm). Green-synthesized ZnO NPs exhibited superior antimicrobial, anti-diabetic, and anticancer activity (MCF-7 cell line) compared to chemically synthesized NPs, with high α-amylase inhibition (84.37%) and cytotoxicity (81.75 µg/mL), demonstrating the efficacy of eco-friendly synthesis.

Item Type: Article
Subjects: Pharmacology, Toxicology and Pharmaceutics > Pharmacology
Divisions: Arts and Science > Vinayaka Mission's Kirupananda Variyar Arts & Science College, Salem > Chemistry
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 02 Dec 2025 09:12
URI: https://vmuir.mosys.org/id/eprint/2743

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