Reconstructive surgery of the corners of the mouth, buccal mucosa, and buccal skin after tumor resection for buccal mucosal squamous cell carcinoma is challenging. This case report presents reconstruction using an extended upper lip flap combined with an Estlander flap and a free anterolateral thigh flap in a 70-year-old man. At 24 months follow-up, the patient had normal speech, optimal lip sensation, and no fluid leakage. This method is a valuable option for wide excision defects around the mouth.