Comparison of post operative analgesia following intraperitoneal instillation of ropivacaine with or without dexamethasone for patients undergoing laparoscopic surgeries

Rahman, Adibur and Ummer, Sadia and S, Kamaludeen and K, Cheran (2025) Comparison of post operative analgesia following intraperitoneal instillation of ropivacaine with or without dexamethasone for patients undergoing laparoscopic surgeries. Perioperative Care and Operating Room Management, 38. ISSN 24056030

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Abstract

Aim: To analyse how combining ropivacaine with dexamethasone in multimodal analgesia amplifies pain management and decreases postoperative discomfort (including nausea, vomiting, and rescue analgesia use) compared to using ropivacaine alone in patients undergoing laparoscopic surgery, with a focus on improving recovery outcomes. Results: The initial patient distribution between groups showed no significant difference, our study highlighted substantial differences in key outcomes. Patients receiving multimodal analgesia (ropivacaine with dexamethasone) had significantly less postoperative nausea, vomiting, lower pain scores (VAS), decreased need for rescue analgesia, and longer intervals before requiring additional pain relief compared to those receiving ropivacaine alone. Conclusion: Combining ropivacaine with dexamethasone for laparoscopic surgery patients gives superior pain relief compared to using ropivacaine alone. This dual approach not only reduces pain more effectively but also reduces nausea, vomiting, and the use of additional pain medication. It aims to enhance postoperative comfort and expedite recovery for patients undergoing these procedures." © 2025 Elsevier B.V., All rights reserved.

Item Type: Article
Additional Information: Cited by: 0
Uncontrolled Keywords: dexamethasone; ropivacaine; adverse drug reaction; aged; analgesia; analgesic activity; clinical trial; comparative study; complication; controlled study; drug therapy; human; intravenous drug administration; laparoscopic surgery; laparoscopy; major clinical study; male; nausea and vomiting; postoperative analgesia; postoperative nausea and vomiting; review; side effect; surgical patient
Subjects: Medicine > Anaesthesiology and Pain Medicine
Divisions: Medicine > Vinayaka Mission's Kirupananda Variyar Medical College and Hospital, Salem > Medicine
Depositing User: Unnamed user with email techsupport@mosys.org
Date Deposited: 26 Nov 2025 09:44
Last Modified: 26 Nov 2025 09:44
URI: https://vmuir.mosys.org/id/eprint/263

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