The existing study of the paper using chemical reaction examines the consequences of thermal and mass transferal on MHD Alumina nanofluid energy passed over an oscillatory plate by radiation. Using similarity transformations, the governing equations are reformed into dimensionless equations and solved through Laplace Transformation. The effects of parameters in radiation (R), Schmidt number (Sc), Prandtl number (Pr), magnetic parameter (M), chemical Reaction Parameter (Kc), solid volume fraction (φ), thermal Grashof number (Gr), mass Grashof number (Gc), phase angle (ω) are scrutinized in velocity, temperature, and concentration forms. The depicted charts are shown the enhancement of the velocity, temperature, and concentration. It observes that an increment of magnetohydrodynamic diminishes the velocity, an increment of thermal and mass Grashof number stand out towards the increase through the velocities, and increasing radiation reduces a temperature. An increment of Schmidt number diminishes the concentration of the Alumina nanofluid. The Concentration of the fluid decreases as an increment of chemical reactive parameters. The increment in time directs to increase the Nusselt number along with the Sherwood number. The skin friction Coefficient improvements with accumulative values of mass grashof number and radiation. © 2023 Elsevier B.V., All rights reserved.