Unmanned Aerial Vehicles (UAVs) gather data efficiently for power line inspection. Anomaly detection is essential for power infrastructure dependability and security. It proposes a Cloud-Enabled Isolation Forest (CEIF) method for UAV-based power line inspection. It improves the isolation forest algorithm's efficiency and scalability in cloud computing. It can process huge UAV inspection datasets by dispersing cloud computing. The technique, which effectively isolates anomalies, is applied to the cloud for fast power line inspection and anomaly identification. It describes the CEIF system's cloud service integration and distributed computing algorithm optimization. Real-world UAV-based power line inspection datasets show it can accurately detect abnormalities with low false-positive rates. It is scalable and robust for improving power infrastructure dependability and security. It allows cloud services to deploy real-world settings to implement different inspection scales. © 2024 Elsevier B.V., All rights reserved.