Hospital readmissions affect healthcare systems globally, increasing costs and morbidity. Readmissions must be predicted and prevented to improve patient outcomes and save healthcare costs. This research leverages the Internet of Things (IoT) sensor data and Logistic Regression (LR) to reduce hospital readmissions using predictive analytics. Patient health data from IoT devices during and after hospitalization is used in the paper. Heart rate, blood pressure, and oxygen saturation are constantly monitored. LR is used to examine this dataset and create a prediction model. The LR algorithm trains us to recognize IoT sensor data patterns and correlations that indicate readmission risks. Our methodology provides developed risk estimates incorporating patient-specific parameters, including age, multiple illnesses, and medical history. The temporal data permits dynamic predictions, considering patient health changes over time. This research detected hospital readmission risk with promising accuracy. These predictions allow healthcare practitioners to proactively intervene and deliver targeted treatments, including prescription modifications, lifestyle advice, and follow-up consultations to decrease readmission. This proactive strategy may improve patient outcomes and save healthcare expenses. © 2024 Elsevier B.V., All rights reserved.