This paper focuses on the phytoconstituents contained in herbal plant extracts and presents them in the form of a herbal microgel with an aim to target rheumatoid arthritis. The study starts from the collection, followed by authentication of the selected medicinal plant, extraction through solvents of the whole plant, and simultaneous phytochemical analysis performed with morphological characterization of the selected extract. The consequent phase forms a specialized gel formulation employing synthetic polymers. The prepared herbal microgel is put through comprehensive evaluation that would include the study of short-term stability as per ICH guidelines No: Q1A. This research offers a promising approach towards an effective and natural remedy for rheumatoid arthritis. © 2025 Elsevier B.V., All rights reserved.