Gnanasigamani, John Peter and Balasubramanian, Arunkumar and Rathnasabapathy, Brindha and Pandian, Naveena and Periasamy, Panneerselvam and Choudhary, R. Arbind Kumar (2025) Influence of BIS monitoring, obesity severity and anesthetic agents on recovery outcomes in obese patients undergoing laparoscopic surgery: A multivariate analysis. Anaesthesia, Pain and Intensive Care, 29 (3). 665 - 673. ISSN 16078322; 22205799
Full text not available from this repository.Abstract
Background & objective: Bispectral Index (BIS) monitoring is widely used to optimize anesthetic depth, but its impact on perioperative recovery outcomes in obese patients undergoing laparoscopic surgery remains unclear. This study evaluates the role of BIS monitoring in postoperative recovery, anesthetic consumption, and hemodynamic stability in this population. Specifically, this study aimed to determine whether BIS monitoring reduces anesthetic consumption, shortens recovery times, improves hemodynamic stability, and enhances patient satisfaction compared to standard anesthesia management. Methodology: This prospective, randomized controlled trial included 130 obese patients (BMI ≥ 30 kg/m2) undergoing laparoscopic cholecystectomy, hernia repair, or sleeve gastrectomy. The patients were randomized into BIS-monitored (n = 64) and Non-BIS (n = 66) groups. Primary outcomes included time to emergence, time to extubation, and the Post-anesthesia Care Unit (PACU) stay. Secondary outcomes assessed anesthetic consumption, hemodynamic stability, postoperative complications, and patient satisfaction. Results: BIS monitoring significantly reduced time to extubation (11.56 ± 4.29 vs. 12.80 ± 4.40 min, p = 0.025) and PACU stay (59.00 ± 17.65 vs. 60.95 ± 17.32 min, P = 0.041). No significant differences were observed in MAP, HR, or anesthetic consumption (P > 0.05). Postoperative complications were comparable between groups, but patient satisfaction scores were slightly higher in the BIS group (8.35 ± 1.60 vs. 7.90 ± 1.88, P = 0.078). Conclusion: BIS monitoring significantly improves postoperative recovery by reducing extubation time and PACU stay, but does not significantly alter intraoperative hemodynamic stability or anesthetic consumption. These findings suggest that BIS monitoring may enhance postoperative recovery in obese patients undergoing laparoscopic surgery. Further research is needed to assess its impact in more complex surgical settings. © 2025 Elsevier B.V., All rights reserved.
| Item Type: | Article |
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| Additional Information: | Cited by: 0; All Open Access; Gold Open Access |
| Uncontrolled Keywords: | desflurane; propofol; sevoflurane; adult; anesthesia; Article; bispectral index; controlled study; delirium; female; follow up; hernia repair; human; hypotension; laparoscopic cholecystectomy; laparoscopic surgery; major clinical study; male; multivariate analysis; nausea; obese patient; obesity; patient satisfaction; patient selection; perioperative complication; postoperative complication; postoperative nausea and vomiting; randomized controlled trial; recovery room; vomiting |
| Subjects: | Health Professions > Medical Terminology |
| Divisions: | Medicine > Aarupadai Veedu Medical College and Hospital, Puducherry > Anaesthesiology |
| Depositing User: | Unnamed user with email techsupport@mosys.org |
| Date Deposited: | 25 Nov 2025 05:58 |
| Last Modified: | 25 Nov 2025 05:58 |
| URI: | https://vmuir.mosys.org/id/eprint/162 |
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