Cytokine levels in Type-2 Diabetes Mellitus (T2DM) Patients with Asymptomatic Bacteriuria (ASB) in Northern Andhra Pradesh

Dimensions

Sagar, K.V.S.B. Vidya and Jyotsna, P. Sarat and Sethumadhavan, K. and Bandaru, Narasinga Rao (2024) Cytokine levels in Type-2 Diabetes Mellitus (T2DM) Patients with Asymptomatic Bacteriuria (ASB) in Northern Andhra Pradesh. Journal of Pure and Applied Microbiology, 18 (2). pp. 1246-1252. ISSN 09737510

Full text not available from this repository.

Abstract

Diabetes is a systemic inflammatory condition. The modulation of cytokine levels caused by Asymptomatic Bacteriuria (ASB) infection can lead to altered inflammatory status in various tissues and may affect their homeostasis and function. We aim to estimate the cytokine (IL-6, TNF-α and IL-10) levels in serum of diabetic individuals with and without ASB to study their clinical significance. The current study evaluates the role of cytokines in inflammation caused due to ASB in T2DM patients. Increase in IL-6 and TNF-α levels may indicate renal tissue damage caused due to inflammation by ASB. Whereas increased IL-10 levels is a possible indicator of persistent infection with bacteria which may lead to diabetic renal disease. © 2024 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects: Biochemistry, Genetics and Molecular Biology > Clinical Biochemistry
Divisions: Medicine > Aarupadai Veedu Medical College and Hospital, Puducherry > Microbiology
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 27 Nov 2025 06:04
URI: https://vmuir.mosys.org/id/eprint/1540

Actions (login required)

View Item
View Item