The effect of intraoperative low-dose ketamine versus dexmedetomidine infusion on postoperative bowel recovery in patients undergoing gastrointestinal malignancy surgeries: Placebo-controlled, randomized trial

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Kumar, Sabari K. and Misra, Satyajeet and Behera, Bikram K. and Singh, Neha and Muduly, Dillip K. and Srinivasan, Anand (2024) The effect of intraoperative low-dose ketamine versus dexmedetomidine infusion on postoperative bowel recovery in patients undergoing gastrointestinal malignancy surgeries: Placebo-controlled, randomized trial. Journal of Anaesthesiology Clinical Pharmacology, 41 (1). pp. 145-150. ISSN 0970-9185

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Abstract

This randomized, placebo-controlled study compared the effects of low-dose intraoperative ketamine and dexmedetomidine on postoperative bowel recovery in 84 patients undergoing open gastrointestinal malignancy surgery. Primary outcome measures (time to first flatus/stool) showed no significant differences among groups. Intervention groups had lower pain scores and reduced analgesic requirements. The study concludes that low-dose ketamine or dexmedetomidine reduces pain but does not accelerate bowel recovery after GI surgery.

Item Type: Article
Subjects: Health Professions > Complementary and Manual Therapy
Divisions: Arts and Science > Vinayaka Mission's Kirupananda Variyar Arts & Science College, Salem > Computer Science
Depositing User: Unnamed user with email techsupport@mosys.org
Date Deposited: 25 Nov 2025 08:37
Last Modified: 25 Nov 2025 08:37
URI: https://vmuir.mosys.org/id/eprint/1043

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