Dimensions
DimensionsDevi, Sumithra and Kumar, M (2025) Design, Synthesis, and Evaluation of Erlotinib–Metal Complexes for Enhanced Anticancer Efficacy. International Journal of Drug Delivery Technology. ISSN 09754415
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Official URL: https://doi.org/10.25258/ijddt.15.3.33
Open Access PDF Link: https://doi.org/10.25258/ijddt.15.3.33
Abstract
This study explored the formation of metal complexes of Erlotinib with Cu, Fe, Zn, Mg, and Mn to improve solubility, bioavailability, and overcome resistance. Characterization via UV-Vis, FTIR, and mass spectroscopy confirmed successful coordination. Metal complexation altered Erlotinib's electronic environment, suggesting potential improvements in pharmacological properties and therapeutic efficacy for NSCLC and pancreatic cancer.
| Item Type: | Article |
|---|---|
| Subjects: | Biochemistry, Genetics and Molecular Biology > Cancer Research |
| Divisions: | Pharmacy > Vinayaka Mission's College of Pharmacy, Salem > Pharmacy |
| Depositing User: | Unnamed user with email techsupport@mosys.org |
| Date Deposited: | 25 Nov 2025 08:46 |
| Last Modified: | 25 Nov 2025 08:46 |
| URI: | https://vmuir.mosys.org/id/eprint/1004 |
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